The influence of conservative surgical practices for malignant ovarian germ cell tumors
نویسندگان
چکیده
منابع مشابه
Clinical characteristics of malignant ovarian germ cell tumors
This study was aimed to investigate the clinical characteristics, treatment and prognosis effect of malignant ovarian germ cell tumors (MOGCTs). A total of 39 patients with MOGCTs treated at Gynecology Obstetrics in Tianjin Central Hospital were enrolled from January 1999 to November 2009 in this study. All the patients underwent pathological examination and diagnosis was confirmed. We used uni...
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Malignant ovarian germ cell tumors (OGCTs) include immature teratomas (ITs), dysgerminomas (DGs), endodermal sinus tumors (ESTs), choriocarcinomas, and embryonal carcinomas. Knowledge about the genetic changes associated with malignant OGCT development is sparse. We therefore analyzed 25 OGCTs (12 DGs, 4 ESTs, and 9 ITs) for gains and losses by comparative genomic hybridization. In total, more ...
متن کاملMolecular Characteristics of Malignant Ovarian Germ Cell Tumors and Comparison With Testicular Counterparts: Implications for Pathogenesis
This review focuses on the molecular characteristics and development of rare malignant ovarian germ cell tumors (mOGCTs). We provide an overview of the genomic aberrations assessed by ploidy, cytogenetic banding, and comparative genomic hybridization. We summarize and discuss the transcriptome profiles of mRNA and microRNA (miRNA), and biomarkers (DNA methylation, gene mutation, individual prot...
متن کاملOvarian stromal and germ cell tumors.
Cancers arising from the stromal and germ cell layers of the ovary are rare, heterogeneous, difficult to study, and require specialized multidisciplinary management. We present a clinically relevant review of the literature of these malignancies, with particular emphasis on the more typical presentations. These tumors more commonly present in younger patients and have a high cure rate. They are...
متن کاملThe significance of comprehensive staging surgery in malignant ovarian germ cell tumors.
OBJECTIVE To evaluate the clinical significance of fertility-preserving comprehensive staging surgery (CSS) in the treatment of malignant ovarian germ cell tumors (MOGCTs). METHODS A total of 92 cases of MOGCTs were retrospectively reviewed. RESULTS Forty-six patients (50%) received CSS, which includes ipsilateral adnexectomy+omentectomy+retroperitoneal lymphadenectomy (appendectomy and mul...
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ژورنال
عنوان ژورنال: Journal of Surgical Oncology
سال: 2008
ISSN: 0022-4790
DOI: 10.1002/jso.21079